New Paper

Research article published in Nat. Struct Mol. Biol.

Posted by Jean-Christophe Aude the 3rd Jul 2024

"cBAF generates subnucleosomes that expand OCT4 binding and function beyond DNA motifs at enhancers"

Marina C. Nocente, Anida Mesihovic Karamitsos, Emilie Drouineau, Manon Soleil, Waad Albawardi, Cécile Dulary, Florence Ribierre, Hélène Picaud, Olivier Alibert, Joël Acker, Marie Kervella, Jean-Christophe Aude, Nick Gilbert, Françoise Ochsenbein, Sophie Chantalat & Matthieu Gérard
Nat Struct Mol Biol 2024 Jul 02

Great work from Matthieu group. My contribution was to design computational tools for the bioinformatic analyses. The most used in this article is exPATT a program to dected binding motifs in genomes using a thresholded PWM matching algorithm. The code is available on github: https://github.com/jcaude/exPATT